With such an acceptable and efficacious strategy, the challenge then became how best to maintain and sustain the testing services, beyond the confines of a pilot study.

During qualitative work with staff, it became apparent that there were barriers to sustained testing in a number of domains: training needs for nonspecialist staff in the provision of routine HIV testing; resource implications – pressures of time, departmental stressors and targets; and the burden of results management. Conversely, there was broad support from staff for routine testing as an effective strategy to identify HIV infections, and as a method by which HIV testing could be normalized and destigmatized [7]. This short report details our experiences selleckchem of maintaining a sustainable, routine HIV testing programme in one of the original study settings: the ED. We aimed to develop and deliver a sustainable model of HIV testing in the Silmitasertib nmr ED of Chelsea and Westminster Hospital, situated in an area with a local diagnosed HIV prevalence of 0.83% (2009) [8]. We aimed to produce

a model of testing that replicated the success of the HINTS study model, but with provision of testing by ED staff themselves. We wished to employ sustainability methodology to refine the service in an iterative fashion in response to key outcome measures. A period of consultation between key stakeholders (ED staff and local sexual health staff) defined the model of delivery. All attending patients fulfilling the inclusion criteria were to be offered an HIV test by ED staff, the inclusion criteria being (i) not known to be HIV-positive, (ii) accessing the health care setting for the first time after the initiation of testing, (iii) aged 16–65 years, and (iv) able to consent to a test. Initially, ED doctors only offered the tests, but this was later extended to involve ED nursing staff (see ‘Results’). Latterly, the upper age limit was also removed in response to patient and stakeholder feedback. A leaflet was provided and verbal Nutlin-3 molecular weight consent was obtained prior to HIV testing. Delivery of HIV testing was in line with published national guidelines

[3], and thus verbal consent only to an HIV test was deemed sufficient, and in line with good clinical practice in the UK. The leaflet was available in multiple languages. All staff delivering testing received focussed and didactic competency-based training from sexual health staff. Results governance and delivery were managed by the local sexual health service. Patients with a reactive HIV test were recalled to undergo confirmatory HIV testing. A helpline number was provided and patients could access their results by telephone or e-mail, and sexual health counsellors were available to all patients upon request. Initially, oral fluid-based HIV testing was used, and was performed using a fourth-generation assay on a modified platform to detect HIV-1 antibodies. The technique and its validation are described elsewhere in this supplement.