In the linear regression analysis, age (beta = -0.628, p = 0.034) and lean mass 12 months after surgery (beta = 0.424, p = 0.021) were found to be the main determinants of femoral neck BMD. Age (beta = -0.765, p = 0.025), menopause (beta = -0.898, p = 0.033), and lean mass (beta = 0.615, see more p = 0.023) were determinants of BMD at the lumbar spine. No influence was found between low bone mass and type of surgery, plasma PTH, 25(OH) D-3, or IGF-I. The effect of RYGB and SG on BMD was comparable a year after surgery. Menopausal women were at a higher risk of having low bone mass, but the presence of osteoporosis was uncommon.”
“A nonconventional approach to the measurement of succinate transport

through plasmalemma is proposed. It is based on the conditions in which the succinate oxidation rate is limited by transport through plasmalemma. Impermeable specific inhibitor of plasmalemma dicarboxylate transporter was employed as a tool to optimize conditions for the transport activity assay. For this purpose yeast culture was grown in synthetic medium. We selected conditions empirically. After aerobic preincubation of S. cerevisiae cells at 0 degrees C (instead of incubation at 15 degrees C), the rate of endogenous

respiration decreased substantially and was stabilized during EVP4593 research buy measurements at a level that was five times lower than oxidation rates in the presence of exogenous substrate. Linearity of Dixon plots for succinate oxidation depression by impermeable O-palmitoyl-L-malate is a test for selected conditions of measurement of plasmalemmal succinate transport. This approach allowed for the reproducible determination of K,,, for the dicarboxylate transporter (7.3 +/- 2.1 mM) within a half-hour period. The advantages and drawbacks of this fast, but indirect, assay of slow

substrates transport into the cell are compared with conventional methods.”
“We present a patient with atrial fibrillation (AF) in whom a left atrial (LA) thrombus might have formed during laparotomy despite bridging anticoagulation therapy. No evidence of thrombus was detected by transesophageal echocardiography (TEE) at the start of surgery; however, a thrombus measuring 13 x 10 mm ATG-016 was found in the LA appendage by the end of the procedure, suggesting that thrombus might develop intraoperatively in patients with AF even when bridging anticoagulation is properly established. Intraoperative TEE can assist in detecting intracardiac thrombus in patients with AF regardless of their anticoagulation status and provides a tool for intervention to prevent systemic embolization.”
“Aim: To analyze the presence of Y chromosome microdeletions in males of Mexican couples with idiopathic recurrent pregnancy losses (RPL). Methods: Seventy-one males from couples with RPL and 66 fertile males as controls were studied. DNA was isolated from peripheral lymphocytes and used to run multiplex polymerase chain reactions.