1-99 6), specificity 99 4% (95% CI 98 1-99 9), and negative predi

1-99.6), specificity 99.4% (95% CI 98.1-99.9), and negative predictive value 99.6% (95% CI 98.4-99.9). The intraclass correlation between CTA and DSA measurements was 0.96 (95% CI 0.95-0.97). Five of 57 patients underwent intracranial stenting procedures KU-55933 mouse during the study period. All 5 lesions were correctly characterized as having >70% stenosis on CTA.

Of the remaining 52 patients, none had clinical management change based on DSA findings. Conclusions: CTA has a high sensitivity and specificity compared to DSA to diagnose intracranial stenosis. The addition of DSA to CTA may not affect clinical management in most patients with suspected stenosis.”
“Objective: To identify clinical factors associated with prolonged recovery after superior canal dehiscence surgery.

Study Design: Retrospective review.

Setting: Tertiary care academic medical center.

Patients: Thirty-three patients that underwent surgery for SCDS were identified from a database of 140 patients diagnosed with SCD (2000-2010) at the Massachusetts Eye and Ear Infirmary (U.S.A.). The diagnosis of SCDS was based on clinical signs and symptoms,

audiometric and vestibular Selleckchem Fer-1 testing and high-resolution temporal bone computed tomography.

Intervention: For the primary repair, the superior canal was plugged in 31 patients through a middle fossa craniotomy approach and in 1 patient through a transmastoid approach. A-1210477 solubility dmso In 1 patient, the SCD was resurfaced through a middle fossa craniotomy approach.

Main Outcome Measures: Postoperative clinical signs and symptoms and factors that may influence duration of disequilibrium after surgery.

Results: Thirty-three patients (15-71 yr; mean, 43 yr) underwent surgery for SCDS on 35 ears (2 bilateral). Mean follow-up was 28.7 months (range, 3 mo to 10 yr); 33 of

33 (100%) patients experienced initial improvement of the chief complaint. Three patients required revision surgery, improving symptoms in 2 patients. Six patients had dizziness lasting more than 4 months postoperatively, and all had bilateral SCD, migraines, and a dehiscence of 3 mm or greater.

Conclusion: Surgical plugging of SCD is an effective management option to provide long-term improvement of the chief complaint in SCDS patients. Patients with bilateral SCD, a history of migraines, and larger defects may be at risk of prolonged recovery and should be appropriately counseled.”
“BACKGROUND: Sacral colpopexy is an effective, durable repair for women with apical vaginal or uterovaginal prolapse. There are few reports of serious complications diagnosed in the remote postoperative period.

CASE: A 74-year-old woman presented 8 years after undergoing posthysterectomy abdominal sacral colpopexy using polypropylene mesh. Posterior vaginal mesh erosion had been diagnosed several months before presentation.

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