100, 102 and 106 Miszko et al.101 evaluated 16 weeks of resistance

training in community-dwelling older adults. Individuals were randomly assigned to either the power training (high-velocity) group or the traditional strength training group. Both groups performed seven of the same exercises for three sets of six to eight repetitions, but with 40% and 80% of one-repetition maximums for power training and traditional strength training, Galunisertib datasheet respectively. For the power training group, the concentric and eccentric phases were 1 s and 2 s in duration, respectively. For the traditional strength training group, the concentric action was performed for 4 s and the eccentric action was performed in a slow and controlled manner. Following the intervention, overall physical function in the power training group was significantly greater than in the strength training group (p = 0.033), as well in specific domains of balance (p = 0.013), INCB018424 endurance (p = 0.026), and upper body flexibility (p = 0.045). Interestingly, the change in physical function was not significantly correlated to the change in power (r = 0.29) or strength (r = 0.16). 101 Moreover, in older women with functional limitations, high-velocity training and traditional resistance training significantly improved scores on the Short Physical Performance Battery and five chair-stand times, but only the high-velocity group significantly

improved gait speed (p < 0.01) and unilateral stance (p = 0.03). 106 Hence, improvements in physical function in older women following an intervention may be dependent on type of resistance training as well as functional status. It should also be acknowledged that some studies comparing high-velocity training and traditional strength training in older adults reported

that both types of resistance training improved muscle capacity but did not improve physical function.88, 100 and 115 Resminostat Though resistance training is the focus of the current review, it is worth noting that greater amounts of PA, such as walking, are associated with higher physical function statuses in older adults.109 Specifically, moderate-intensity PA (e.g., normal walking or gardening) sustained for a moderate-to-high duration can reduce functional limitations by 50% in older adults.109 In conclusion, decades of research have reported the positive impacts of resistance training on body composition,80 and 81 muscle strength,83, 86, 88, 89, 90 and 91 muscle power,17, 88, 90, 100, 101, 102, 103, 104 and 105 and subsequently, physical function,17, 88, 100, 101, 103 and 106 in older adults. However, the exact mechanisms mediating these relationships have not been elucidated. Thus, even when improvements in physical function have been observed post-intervention, it is difficult to understand the role of muscle strength and muscle power in facilitating this improvement.