5×10(-10)tau(-1/2) until 30 s These results, similar to those pu

5×10(-10)tau(-1/2) until 30 s. These results, similar to those published in the literature by others groups, prove the potential of our original microcell INCB024360 cell line technology in view of the development of high-performance chip scale atomic clocks. (C) 2011 American Institute of Physics. [doi:10.1063/1.3530951]“

To assess the reliability of and correlation between 2 contrast sensitivity tests in normal eyes and eyes with cataract.

SETTING: Department of Ophthalmology, Yonsei University Hospital, Seoul, Korea

METHODS: The Vision Contrast Test System (wall-chart test) and Optec 6500 system (view-in test) were used to measure contrast sensitivity in normal eyes at 2 visits separated by 2 weeks and in eyes with cataract before and 2 months after cataract surgery. The test-retest reliability Sapanisertib and correlation were calculated by the intraclass correlation coefficient (ICC), coefficient of repeatability (COR), and 95% range of difference using the Bland-Altman method.

RESULTS: The study evaluated 40 normal eyes of 20 subjects and 44 eyes of 38 cataract patients The repeatability of the 2 test methods was generally acceptable The view-in test performed better than the wall-chart test in the ICC analysis (0 85 versus 0.65) but not in the COR analysis (+/- 0 20 log versus +/- 0.27 log) Correlation between the 2 tests was poor in both groups of eyes The ceiling effect

was greater with the wall-chart test. The floor effect occurred mainly in patients with cataract, in which it was greater preoperatively than postoperatively, at high frequency, and with the view-in test

CONCLUSION: Based on the ceiling and floor effect, the view-in test is better for detecting subtle contrast sensitivity changes in normal or near-normal eyes and the wall-chart test is useful in eyes with compromised vision”
“A thermosensitive

Fosbretabulin chemical structure grafted hydrogel was investigated for heating-activated drug release. The hydrogel was created by grafting oligomers of N-isopropylacrylamide-co-acrylamide (AAm) to a poly-(2-hydroxyethyl methacrylate), or PHEMA, hydrogel. N-Isopropylacrylamide-co-AAm oligomers were synthesized with a range of compositions to raise the lower critical solution temperature (LCST) above physiological temperature. PHEMA hydrogels with these thermosensitive grafts were synthesized by free-radical solution polymerization, using an acrylated version of the oligomers. The oligomers were characterized for their molecular weight, LCSTs, and rate of response to a change in temperature. With the flexibility in tuning their properties by varying reaction parameters, these oligomers present possibilities in several fields, including drug delivery. The impact of cross-linking agent type and the amount and presence of grafts on the polymer network structure was found by determining the hydrogel mesh sizes.

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