After Karzon arrived, he successfully built a coalition of advocates to build a Children’s Hospital in Nashville. Through acumen, foresight and equanimity, he brought together the university and a myriad of community resources around a common vision that is now the Monroe Carell Jr. Children’s Hospital at Vanderbilt [1]. In addition to Karzon’s influence on children’s health through basic research Selleck MI-773 and building specialized care facilities, he also was involved in vaccine policy and regulation. His 1977 NEJM editorial “stressed the need for an equitable system of compensation for unavoidably injured vaccine recipients and for indemnification of

physicians and manufacturers…” [2]. In a follow-up 1984 NEJM editorial he outlined the importance and need for a national

compensation program for vaccine-related injuries that preceded the 1986 National Childhood Vaccine Injury Compensation Act [3]. He understood that recognizing and compensating the few individuals who suffered from vaccines would ensure that the enormous public health benefit provided by widespread vaccination would be protected. This is equally true today and the tremendous gains in public health that have been made because routine childhood vaccination would be threatened without this recognition and provision. Consistent with Karzon’s own values and ethics,

this law advocates Obeticholic Acid price the good for children, families, and the public health. Karzon was also a frequent Unoprostone advisor to the FDA on issues of vaccine safety and his extremely conservative positions helped raise the regulatory standards for vaccine safety that benefit us today. The exceptional critical thinking and persistence that Karzon applied to all aspects of his personal and professional life made a lasting impression on his colleagues and students. Truth was his ultimate value, and as applied to vaccine development, he was very clear that if you do not get it right, it will not work. Robert M. Chanock, who was a protégé of Albert Sabin, became an iconic figure in virology. He is credited with the discovery of the microbial basis of many common infectious diseases. He uniquely contributed to all aspects of our knowledge about these pathogens and the diseases they cause, and made singular advances toward their control and prevention. Chanock attended the University of Chicago for undergraduate studies and after being drafted into the military accepted an offer to medical school at Chicago, receiving his MD in 1947. After a one-year internship in Oakland, CA, he returned to the University of Chicago to complete a two-year residency in pediatrics.