The curative effect and satisfaction level after six months of therapy in 4 teams had been recorded and compared. The masticatory purpose (chewing effectiveness, bite force), gingival function[plaque index(PLI), gingival index(GI) and sulcus bleeding index(SBI)], gingival crevicular substance inflammation-related indicators[tumor necrosis aspect alpha(TNF-α), interleukin-6(IL-6), aspartate aminotransferase(AST) and alkaline phosphatase (alkaline phosphatase, ALP)] pre and post treatment were calculated and compared in 4 groups. Analytical analysis had been carried out with Sromium alloy group≈nickel-chromium alloy team. There was no significant difference in repair stability and color pleasure in 4 groups(P＞0.05), but there was clearly factor in marginal fitness and sensitiveness satisfaction in 4 groups(P＜0.05). Pure titanium, cobalt-chromium alloy, nickel-chromium alloy and zirconium dioxide can be utilized for the treatment of GMO biosafety dentition flaws, in addition they all can buy satisfactory chewing function. In inclusion Sorafenib D3 ic50 , zirconium dioxide renovation gets the effect of improving gingival purpose and inflammation-related signs of gingival crevicular liquid with a wider application prospect.Pure titanium, cobalt-chromium alloy, nickel-chromium alloy and zirconium dioxide can be utilized for the treatment of dentition defects, and additionally they all can acquire satisfactory chewing purpose. In addition, zirconium dioxide renovation has the effect of increasing gingival function and inflammation-related signs of gingival crevicular fluid with a wider application possibility. To evaluate the medical effectation of total denture restoration in edentulous clients utilizing additional functional impression. Complete denture renovation was done in 433 edentulous customers utilizing additional practical impression. The Geriatric Oral Health Assessment Index (GOHAI) was used to gauge clients’ oral health-related standard of living severe alcoholic hepatitis pre and post restoration. All clients had been divided in to 3 teams based on whether they had a history of denture restoration no denture group(ND)，removable limited denture group(RPD), full denture group(CD). In CD team, 30 customers had been expected to chew two-colour gum. The SDhue value ended up being evaluated by utilizing ViewGum software. SPSS 26.0 program was useful for data evaluation. Additional practical impression is easy and quickly, and may improve the satisfaction of clients after complete denture restoration.Additional functional impression is simple and quickly, and can enhance the satisfaction of patients after full denture renovation. A total of 55 mandibular 2nd molars from 38 patients which came across the criteria for inclusion at Nanjing Stomatological Hospital, Affiliated Stomatological Hospital of healthcare School of Nanjing University from January 2020 to July 2021 were analyzed．From this sample, ten teeth was addressed, while another 45 of these maybe not. CT pictures of the teeth had been reestablished by Mimics computer software 20.0. Then we made a section every 1mm perpendicular to the long axis of the teeth from apex to pulp floor. The first piece from apex to pulp chamber was named the piece 1. Over the slice 1 to crown 1 mm had been called piece 1, and so forth. The wall depth at different locations of all of the slices had been measured. The information was entered into SPSS 20.0 software program for evaluation. The lingual canal walls’ width in apex third reason behind C-shaped root canal had been thin before channel preparation. The buccal wall space’ width in apex 1 / 2 root and the lingual canal walls’ in apex two-thirds of cause of C-shaped root channel had been slim after channel planning.The lingual canal walls’ width in apex 3rd root of C-shaped root channel had been slim before canal planning. The buccal wall space’ width in apex one half root and the lingual canal wall space’ in apex two-thirds of reason behind C-shaped root canal were slim after canal preparation. A total of 172 customers with HIMTM were randomly split into experimental group and routine team with 86 cases in each group . Lingual wedge-shaped coronectomy ended up being applied when you look at the experimental group and T-shaped coronectomy ended up being applied in routine group. Operation time, intraoperative and postoperative complications had been compared amongst the two groups.The data were examined simply by using SPSS 26.0 software. Lingual wedge shaped coronectomy of HIMTM has significant benefits in the extraction of HIMTM. It could reduce procedure time，broken roots,fracture of lingual plate, postoperative swelling, discomfort and other medical problems.Lingual wedge-shaped coronectomy of HIMTM features significant benefits in the extraction of HIMTM. It could lower procedure time，broken roots,fracture of lingual plate, postoperative swelling, discomfort as well as other surgical complications. A total of 103 customers with OSCC who have been accepted to Shangrao individuals’s medical center from January 2016 to February 2019 were prospectively selected once the research subjects. All customers underwent radical resection of OSCC and were followed up for 3 years. Immunohistochemistry was made use of to detect the positive appearance degrees of RACK1 and EGP40 in cancer tumors cells and adjacent cells. The good phrase of RACK1 and EGP40 in cancer tumors tissues and adjacent areas were contrasted. The relationship involving the good phrase amount of RACK1 and EGP40 in cancer tissues of OSCC clients and clinicopathological variables had been examined.