SSTR2A-positive neuroendocrine tumors may be treatable by SS anal

SSTR2A-positive neuroendocrine tumors may be treatable by SS analogues. Uterine cervical neuroendocrine carcinoma is generally associated with poor prognosis.

We learn more examined the expression of SSTR2A and other neuroendocrine markers [neural cell adhesion molecule (NCAM), chromogranin A, and synaptophysin] by immunohistochemical methods in seven neuroendocrine tumors of the uterine cervix: five small cell carcinomas and two large cell neuroendocrine carcinomas.

SSTR2A was expressed in one small cell carcinoma and two neuroendocrine large cell carcinomas. The cell membrane of cells in these carcinomas showed strong immunohistochemical reactivity for SSTR2A. SSTR2A-positive cases are also frequently positive

for the expression of chromogranin

A. Treatment with SSTR2A may be effective for endocrine tumors. The results indicate the usefulness of SSTR2A analogs for the treatment of some uterine neuroendocrine carcinomas.”
“The obtained spectroscopic data for absorption and scattering characteristics of nanoporous silica in the wavelength range from 0.25 to 7 mu m are analyzed on the basis of the Mie theory. It is shown that aggregates of primary nanoparticles are responsible for relatively high scattering in the short-wave range from 0.25 to 1.4 mu m. But the presence of the aggregates and micron-size cracks in the samples cannot explain unusual behavior of scattering in the long-wave part of the spectral range. The attention dbcAMP of the authors is focused on understanding

of strong scattering peaks observed at exactly the same wavelengths as the infrared absorption peaks of bulk silica: at lambda = 2.9, 5.3, and 6.1 mu m. The known physical effect of “”scattering by absorption”" is considered as a source of these scattering peaks. It means that absorption centers are assumed to be not uniformly distributed CA-4948 in vivo in the nanoporous matrix but collected in some micron-size regions. The estimates based on this hypothesis are supported by the fact that near-infrared absorption peaks are produced by silanol groups which may be nonuniformly distributed in the hydroxylated nanoporous silica. (C) 2010 American Institute of Physics. [doi: 10.1063/1.3374473]“
“Objectives: The objective of this review is to assist the readers, anesthesiologists, intensivists, and emergency physicians in making a more accurate diagnosis of perioperative fever or hyperthermia and subsequently choose the proper course of treatment.

Aim: To identify the many sources of perioperative fever and after a more accurate differential diagnosis, select appropriate treatment options. Most anesthesiologists, intensivists, and emergency physicians are not familiar with an expansive differential of perioperative fever. This article attempts to expose these physicians to that differential diagnosis.

Background: Much of the medical literature has anecdotal reports, small case series, or limited reviews of the possible sources of hyperthermia or fever.

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