The proportional hazard assumption was assessed performing log-log survival curves based on Schoenfeld residuals [20]. Cumulative incidence http://www.selleckchem.com/products/Calcitriol-(Rocaltrol).html of entry into care and death was estimated using the ��stcompet�� command in Stata [21, 22]. The study was approved by the ethical committee of the RDT Institutional Review Board.3. ResultsWe identified 526 children from the VFHCS who were diagnosed with HIV from 2007 to 2012. Three children who were transferred to other ART centres were not included in the analysis. The study included 264 child-years, and, during the study period, nine children died and 38 were LTFU. Among children who died, the median time from HIV diagnosis to death was 1.6 months (interquartile range (IQR), 0.3�C3.6) and, in those who did not enter into care, the median followup was 56 months (IQR, 44.

6�C66.2). The median time from HIV diagnosis to entry into care was 0.2 months (IQR, 0.03�C0.9). Baseline characteristics and multivariable analysis of factors associated with entry into medical care are described in Table 1. The median age at HIV diagnosis was 60 months (IQR, 31.5�C102.4); over half were female, in 98% of them, HIV was vertically transmitted, and in 92%, the HIV diagnosis was made after their mothers were diagnosed with HIV. Over half belonged to BC communities and 63% were living far from town. The majority of children were diagnosed between 2007 and 2009, and over half needed more than one hour to reach the ART centre. Near half of the children had lost one or both of their parents, and the majority of those whose parents were alive were living in a rented house.

Factors associated with delayed entry into medical care were being diagnosed at earlier calendar years, being diagnosed after knowing that the mother was HIV positive, belonging to SC communities, age <18 months, female gender, and living >90 minutes from the ART centre. Those children whose parents were alive and were living in a rented house were at a higher risk of delayed entry into care than those who were living in an owned house. Table 1Baseline characteristics and multivariable analysis of factors associated with entry into care using competing risk regression of 523 children diagnosed with HIV in Anantapur, India.A stacked graph of the status of HIV-infected children since HIV diagnosis is presented in Figure 1. The cumulative incidence of entry into care was 78.

4% (95% CI, 74.6�C81.7) at 3 months, 83.6% (95% CI, 80.1�C86.5) at 6 months, 87.2% (95% CI, 84�C89.8) at 1 year, Carfilzomib 88.9% (95% CI, 85.9�C91.3) at 2 years, 90.3% (95% CI, 87.4�C92.6) at 3 years, 90.7% (95% CI, 87.9�C92.9) at 4 years, 91.1% (95% CI, 88.2�C93.3) at 5 years, and 91.9% (95% CI, 88.7�C94.2) at 6 years. The cumulative incidence of death before entry into care was 1.1% (95% CI, 0.5�C2.4) at 3 months, 1.3% (95% CI, 0.6�C2.6) at 1 year, 1.5% (95% CI, 0.7�C2.