The results demonstrate that a method may perform excellently on average but struggle when used on a number of narrower topics. Topic-adjusted www.selleckchem.com/products/nu7441.html metrics and other topic robust methods have an advantage in such situations. Users of traditional topic-sensitive metrics should be aware of their limitations. (C) 2011 Elsevier Inc. All rights reserved.”
“Experimental accessibility of crystal shape is still limited today. We present a new method for extracting

three-dimensional (3D) crystal shape from measurement data. The algorithm is demonstrated on data obtained by microcomputed tomography (mu CT) for potash alum, although the approach is applicable to any 3D imaging technique and any faceted crystal. First, the crystal face normals are identified using a 3D Hough transform. In a second step, the relationship between the identified and all potentially arising crystal face normals is matched to obtain the relative orientation between the measurement data and the crystal model. The final shape parameters guarantee maintainance of the symmetry of the geometric crystal model and, hence, are compatible with common approaches to model the growth of multifaceted crystals. The procedure can be automated, which opens the

possibility of evaluating full particle size-and-shape distributions, within the discussed limitations concerning crystal quality and sample size.”
“Since its approval in 2011 for patients with recurrent glioblastoma

MEK phosphorylation (GBM), physicians have responded positively to the non-invasive nature of the NovoTTF-100A System device (Novo Cure Ltd, Haifa, Israel), citing significantly less toxicity and a better quality of life profile compared to available conventional therapies. A roundtable discussion (available at: http://education. seminoncol.org/path.php?1399:0:Media:title:bxvcs) was recently convened to provide a knowledge-based perspective surrounding current treatment options for patients with GBM and the clinical challenges Selleckchem OICR-9429 involved with the treatment of recurrent GBM patients who have failed prior therapies. The participating roundtable experts discussed the challenges encountered in managing GBM patients, the current approved treatment options for these patients, the efficacy and safety profile of NovoTTF therapy (TTFields), and its use as a novel treatment modality for recurrent GBM patients.”
“The free vibration analysis of a carbon nanotube (CNT) embedded in a volume element is performed using 3D finite element (FE) and analytical models. Three approaches consist of molecular and continuum mechanics FE methods and continuum analytical method are employed to simulate the CNT, interphase region and surrounding matrix. The bonding between CNT and polymer is treated as non-perfect bonding using van der Waals and triple phase material interaction in first and second approaches.