The authors noted

significant improvements in neurologic function and walk test speeds in experimental versus control groups. The authors conclude that ABT has the potential to promote neurologic recovery and enhance walking ability in individuals Silmitasertib solubility dmso with chronic, motor incomplete SCI. A secondary analysis performed by the authors adds insight into who is likely to benefit most from ABT. ■ SEE THE FULL ARTICLES AT PAGE 2239 AND 2247 The HANDGUIDE study was initiated with the goal of creating a multidisciplinary consensus on treatment guidelines for 5 non-traumatic hand disorders. In this study, Huisstede and colleagues report on the results for carpal tunnel syndrome (CTS). A total of 35 experts including hand surgeons, hand therapists, and physical medicine and rehabilitation physicians participated in the Delphi consensus strategy. Each Delphi round consisted of a questionnaire, analysis, and a feedback report. After 3 Delphi rounds, consensus was achieved selleck chemicals llc on the description, symptoms, and diagnosis of CTS. The experts agreed that instructions combined with splinting, corticosteroid injection, corticosteroid injections plus splinting, and surgery are suitable treatments for CTS. This multidisciplinary treatment guideline may help physicians and allied health care professionals

to provide patients with CTS with the most effective and efficient treatment available. ■ SEE THE FULL ARTICLE AT PAGE 2253 Gerrard and colleagues performed a cross-sectional survey of 7968 community-dwelling adults aged 60 years and older. Interleukin-3 receptor They studied the 20 items in the Functional Status Measure (FSM) in 3 domains (cognitive and social functioning,

lower extremity function, and upper extremity function) and created FSM benchmark curves based on percentiles at each year of age. Model fit of a 20-item functional status measure to a confirmatory factor analysis model was assessed, and functional status benchmarks for age were developed with curves plotting activity difficulty percentiles versus age for the general United States population. The authors conclude that a broad measure of difficulty with functional activities can be meaningfully treated as a 3 domain construct, and that the scores represented by the index measuring this construct can be used to assess functional status using normative values. ■ SEE THE FULL ARTICLE AT PAGE 2264 “
“The prognosis of whiplash-associated disorders (WADs) varies substantially within the population, with recovery rates of 40% to 60% within the first year. Many individuals with WADs report symptoms and disability 1 year after the initial injury.1 and 2 Because of long-term work absence and disability, delayed recovery from WADs causes a substantial burden to individuals and society.3 Several studies4 and 5 have investigated prognostic factors for the clinical course of WADs.