The mean (SD) age of the sample was 53.2 (15.7) years; 45% (n=70) were female; 78% were white, 7% were black, 5% were

American Indian, and 10% were “other” or more than one race. Twenty-five per cent were Hispanic. Approximately 26% of participants (n=41) had a diagnosis of COPD, 28% (n=43) had asthma, 10% (n=16) had heart failure, 16% (n=25) had pneumonia, and 19% (n Inhibitors,research,lifescience,medical =29) had other cardiopulmonary diagnoses. The component structure and domains for the MDP recall ratings were the same as reported previously [28] for the “now” ratings in these ED patients. For the three recall administrations, the Immediate Perception domain (7 items; Cronbach’s α=.89 to .94) and Emotional Response domain (5 items: Cronbach’s α=.81 to .85) jointly accounted for 63% to 71% of item variance (see Additional file 1: Table A1 — Principal components analysis). Means,

SDs, and quartiles for the MDP items and the two mean domain scores for each recall time period are shown in Inhibitors,research,lifescience,medical Table ​Table1.1. Means for the Immediate Perception items were consistently higher than for the Emotional Response items in all three recall assessments (Table ​(Table1).1). The mean domain scores were approximately 2 scale points higher for the Immediate Perception domain compared with the Emotional Response domain in each recall assessment Inhibitors,research,lifescience,medical (Table ​(Table2).2). The Time 0a recall ratings and the concurrently obtained Time 1 “now” ratings were moderately and positively correlated for all items (Immediate Perception items: r=.30 to .45, p<.001; Emotional Response items: r=.46 to .60, p<.001) and domain scores (r=.42, p<.001 for Immediate Perception; r=.61, p<.001 for Emotional Response). Table 1 Descriptive statistics Inhibitors,research,lifescience,medical for recall rating: how breathing felt “when you decided to come Inhibitors,research,lifescience,medical to the ED” Table 2 Within-subjects differences in mean scores for Immediate Perception vs. Emotional Response domains Test–Selleck XAV-939 retest ICCs between recall ratings for the approximate 1-hour interval between Times 0a and 0b (Table ​(Table3)3) ranged from .69 to .86 for the individual items and .92 to .94 for the

two domains. For the 4- to 6-week interval between the initial recall rating and the follow-up visit, ICCs were much lower (.28 to .66 for individual items and.72 to .78 for the two domains). Examination of 95% CIs around ICCs for the two test–retest Cytidine deaminase intervals showed no overlap; therefore, all ICCs were significantly lower for the longer test–retest interval. Table 3 Test–retest reliability of MDP recall ratings (single items and domains) For the test–retest interval during the ED visit (Time 0a to 0b; Figure ​Figure1),1), mean differences for individual items ranged from −0.02 to +0.57 points, with all but two falling between 0.1 and 0.5 points. The mean differences for the two mean domain scores were approximately +0.3 points for Immediate Perception and EmotionalResponse.