Using the age distribution of the Rucaparib mw Oslo population 01.01.1997 as the reference, the age adjusted incidence rates in Harstad were 101.0 and 37.4 per 10,000 in women and men, respectively, compared to 118.0 per 10,000 in women (p = 0.005) and 44.0 per 10,000 in men (p = 0.09) in Oslo [8]. Table 2 Age- and sex-specific annual hip fracture incidence per 10,000 in different regions in Norway Age groups (years) Harstad, Northern Norway (Emaus 2010) Oslo, Norway (Lofthus 2001) South Eastern Norway (Bjørgul 2007) Mid-Norway (Grønskag 2009) Men  50–54 5.8 (1.5, 10.1) 3.9 (0.8, 7.0) 4.2 (1.8, 6.5)    55–59 5.9 (1.2, 10.7) 8.0 (2.5,13.5) 3.0 (1.8, 6.5)    60–64 7.8 (1.5, 14.0) 13.7 (5.6, 21.7) 12.5 (7.3, 17.8)    65–69 31.4 (17.7, 45.2) 25.0 (14.3, 35.7) 15.7 (9.6, 21.9)    70–74 35.7 (20.1, 51.4) 54.6 (38.7, 70.6) 38.9 (29.0, 48.8)    75–79 59.4 (37.0, 81.8) 78.5 (57.2, 99.9) 79.1 (63.7, 94.4)    80–84 124.6

(84.4, 164.7) 166.4 (126.3, 206.6) 141.1 (114.3, 167.9)    85–89 266.7 (167.9, 365.4) 246.8 (173.1, 320.6) 265.2 (210.2, 320.1)    90+ 349.2 (142.8, 555.6) 429.8 Trametinib molecular weight (264.6, 594.9) 325.7 (218.0, 433.3)   Women  50–54 8.7 (3.3,14.1) 5.3 (1.6, 9.0) 3.9 (1.6, 6.2)    55–59 13.3 (6.0, 20.5) 11.4 (5.0, 17.9) 9.9 (5.9, 13.9)    60–64 13.8 (5.6, 21.9) 16.1 (7.9, 24.2) 13.7 (8.4,

18.9)    65–69 31.5 (18.3, 44.6) 40.5 (28.2, 52.7) 32.2 (23.9, 40.6) 21.1 (11.6, 38.1)  70–74 60.7 (42.2, 79.3) 77.1 (61.2, 92.9) 68.5 (56.6, 80.4) 53.3 (43.0, 66.0)  75–79 121.8 (94.1, 149.6) 142.5 (120.9, 164.1) 137.3 (120.3, 154.4) 95.1 (81.6, 110.7)  80–84 274.9 (227.1, 322.7) 282.6 (247.9, 317.4) 236.6 (211.5, 261.6) 170.2 (149.0, 194.4)  85–89 329.3 (257.6, 401.0) 475.5 (417.8, 533.2) 366.8 (326.2, 407.5) 307.4 (267.1, 358.9)  90+ 582.2 (437.2, 727.1) 618.0 (523.7, 712.3) 396.3 (331.3, 461.3) 496.7 (412.4, 598.2) Fig. 2 displays the age-adjusted incidence of hip fractures in women and men in Harstad during 1994–2008 for three different age groups. The age-adjusted GBA3 incidence rates for women were 97.3 and 105.2 per 10,000 in 1994–1996 and 2006–2008, respectively (p = 0.55).